Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25556725 | 0.86 | FBP1 (0.43) | FBP1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL23782372 | 0.83 | HTT (0.43) | FBP1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL25545941 | 0.77 | LMNA (0.48) | FBP1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL18282064 | 0.76 | LMNA (0.42) | FBP1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL25545932 | 0.76 | FBP1 (0.44) | FBP1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL23792283 | 0.75 | PTGDR2 (0.46) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL23792330 | 0.75 | NPC1 (0.43) | FBP1KDM4EALDH1A1POLBPTGDR2 | |
| SCHEMBL23792344 | 0.75 | RAB9A (0.39) | FBP1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL21301127 | 0.74 | KMO (0.44) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL21300927 | 0.74 | MAPK1 (0.44) | MAPTALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178488-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2021-09-10 | — | — | WO | disclosed |