Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30759361 | 0.84 | AAK1 (0.37) | AAK1 | |
| SCHEMBL23610090 | 0.82 | HDAC6 (0.32) | NOS1NOS3NOS2 | |
| SCHEMBL23610091 | 0.82 | HDAC6 (0.32) | NOS1NOS3NOS2 | |
| SCHEMBL19809606 | 0.80 | GABRP (0.35) | MEN1GAAKMT2ACHRNB2CHRNA4 | |
| SCHEMBL19809608 | 0.80 | GABRP (0.35) | MEN1GAAKMT2ACHRNB2CHRNA4 | |
| SCHEMBL23230739 | 0.79 | CTSK (0.34) | NOS1NOS3NOS2CTSK | |
| SCHEMBL18644426 | 0.79 | CPB2 (0.35) | NOS1NOS3NOS2MEN1GAA | |
| SCHEMBL17756070 | 0.79 | PRKCA (0.32) | NOS1NOS3NOS2MEN1GAA | |
| SCHEMBL30207652 | 0.77 | LMNA (0.30) | KMT2A | |
| SCHEMBL6305191 | 0.76 | KMT2A (0.34) | NOS1NOS3NOS2MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3530290-A1 | ALPHA AMINOACID ESTER-DRUG CONJUGATES HYDROLYSABLE BY CARBOXYLESTERASE | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-08-28 | — | — | EP | disclosed |