SCHEMBL21311341

SCHEMBL21311341

O=C1CC(O)c2cccc(Cl)c21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
RECQL P46063 1/20 0.41
POLL Q9UGP5 1/20 0.41
HTR2A P28223 3/20 0.40
HTR2C P28335 3/20 0.40
HTR2B P41595 3/20 0.40
PBRM1 Q86U86 3/20 0.38
CDK4 P11802 1/20 0.36
CCND1 P24385 1/20 0.36
GRIA1 P42261 1/20 0.36
CACNG8 Q8WXS5 1/20 0.36
LDHA P00338 1/20 0.36
LDHB P07195 1/20 0.36
MAPK14 Q16539 2/20 0.35
TTR P02766 1/20 0.35
AADAT Q8N5Z0 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
XBP1 P17861 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12714993 0.78 POLL (0.44) POLLHTR2AHTR2CHTR2BAADAT
SCHEMBL19899064 0.70 NOS3 (0.43) HTR2AHTR2CHTR2BMAPK14AADAT
SCHEMBL19302757 0.70 AR (0.46) KDM4EALDH1A1MAPK1
SCHEMBL30737888 0.70 AR (0.46) KDM4EALDH1A1MAPK1
SCHEMBL2929675 0.70 AR (0.46) KDM4EALDH1A1MAPK1
SCHEMBL11869980 0.70 AR (0.46) KDM4EALDH1A1MAPK1
SCHEMBL5426438 0.68 PBRM1 (0.39) TP53RECQLHTR2AHTR2CHTR2B
SCHEMBL14477617 0.66 DRD2 (0.38) POLLHTR2A
SCHEMBL2817121 0.64 CACNG8 (0.37) TP53HTR2AHTR2CHTR2BPBRM1
SCHEMBL20902858 0.63 HTR7 (0.43) HTR2BPBRM1CACNG8ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019164054-A1 NOVEL COMPOUND, METHOD FOR MANUFACTURING SAME, AND ORGANIC ELECTRONIC ELEMENT USING SAME 한국화학연구원 2019-08-29 WO disclosed