Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | SLC28A1 | O00337 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | GMPS | P49915 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 3/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.33 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311192 | 0.78 | DOT1L (0.37) | ADORA2ASLC28A1ADORA3GMPSPI4KA | |
| SCHEMBL21311216 | 0.77 | ADORA2A (0.47) | ADORA2ASLC28A1ADORA3GMPSPI4KA | |
| SCHEMBL23025515 | 0.77 | ADORA3 (0.53) | ADORA2ASLC28A1ADORA3GMPSPI4KA | |
| SCHEMBL25521510 | 0.77 | ADORA3 (0.53) | ADORA2ASLC28A1ADORA3GMPSPI4KA | |
| SCHEMBL21311154 | 0.76 | ADORA3 (0.47) | ADORA2ASLC28A1ADORA3GMPSPI4KA | |
| SCHEMBL21311217 | 0.76 | ADORA2A (0.47) | ADORA2ASLC28A1ADORA3GMPSPI4KA | |
| SCHEMBL21311468 | 0.76 | ALDH1A1 (0.39) | ADORA2ASLC28A1ADORA3GMPSDOT1L | |
| SCHEMBL21311388 | 0.76 | DOT1L (0.41) | ADORA2ASLC28A1ADORA3GMPSPI4KA | |
| SCHEMBL20097017 | 0.76 | METTL3 (0.39) | ADORA2ASLC28A1ADORA3GMPSPI4KA | |
| SCHEMBL21311475 | 0.74 | ADORA3 (0.39) | ADORA2ASLC28A1ADORA3GMPSPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | POLRMT, EIF2AK2, NSUN3 | ADORA2A 2943/4885SLC28A1 1311/4885ADORA3 2754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.