Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21314953 | 0.88 | KMT2A (0.37) | KDM4EGLP1RKMT2AALDH1A1GABRA2 | |
| SCHEMBL28767771 | 0.86 | KDM4E (0.37) | KDM4EGRK6KMT2AALDH1A1CYP1A2 | |
| SCHEMBL28767778 | 0.86 | KMT2A (0.36) | KDM4EGLP1RKMT2AALDH1A1GABRA2 | |
| SCHEMBL21314973 | 0.77 | KDM4E (0.41) | KDM4EKMT2AALDH1A1CYP1A2GABRG2 | |
| SCHEMBL28767783 | 0.76 | KMT2A (0.37) | KDM4EKMT2AALDH1A1TP53MAPT | |
| SCHEMBL28767754 | 0.74 | GABRG2 (0.37) | KDM4EKMT2AALDH1A1CYP1A2GABRP | |
| SCHEMBL21314967 | 0.72 | RIPK1 (0.33) | ALDH1A1 | |
| SCHEMBL9704109 | 0.69 | GABRB3 (0.56) | KDM4EGLP1RKMT2AALDH1A1GABRP | |
| SCHEMBL34472681 | 0.64 | ALDH1A1 (0.41) | KDM4EKMT2AALDH1A1GABRA2GABRB2 | |
| SCHEMBL34473456 | 0.64 | SMN1; SMN2 (0.60) | KDM4EALDH1A1CYP1A2GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113994970-B | Substituted sulfonamides for combating animal pests | 拜耳公司 | 2023-05-12 | — | — | CN | disclosed |
| US-20220380318-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-01 | — | — | US | disclosed |
| EP-4055010-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | Bayer Aktiengesellschaft (DE) | 2022-09-14 | — | — | EP | disclosed |
| CN-114641467-A | Substituted sulfonamides for controlling animal pests | 拜耳公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-113994970-A | Substituted sulfonamides for combating animal pests | 拜耳公司 | 2022-02-01 | — | — | CN | disclosed |
| EP-3534709-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| EP-3534709-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | BAYER AKTIENGESELLSCHAFT (DE) | 2020-11-03 | — | — | US | disclosed |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | BAYER AKTIENGESELLSCHAFT (DE) | 2020-11-03 | — | — | US | disclosed |
| EP-3534709-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | Bayer Aktiengesellschaft (DE) | 2019-09-11 | — | — | EP | disclosed |
| US-20190269134-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-05 | — | — | US | disclosed |
| US-20190269134-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190269134-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | MLYCD, STOM, DDT | KDM4E 614/4885GRK6 3484/4885GLP1R 124/4885 |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | MLYCD, STOM, DDT | KDM4E 614/4885GRK6 3484/4885GLP1R 124/4885 |
| US-20220380318-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | ATL3, DDT, STOM | KDM4E 434/4885GRK6 3828/4885GLP1R 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.