Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21316424 | 0.85 | GPR35 (0.54) | MAOBMAOAHSD17B10GPR35ALDH1A1 | |
| SCHEMBL21316394 | 0.83 | GPR35 (0.44) | MAOBNPC1RAB9AMAOAGPR35 | |
| SCHEMBL21316426 | 0.76 | MEN1 (0.34) | MAOBMAOAHSD17B10GPR35ALDH1A1 | |
| SCHEMBL21316427 | 0.72 | GPR35 (0.50) | MAOBMAOAHSD17B10GPR35ALDH1A1 | |
| SCHEMBL23155088 | 0.67 | MAOB (0.54) | MAOBMAOAGPR35ALDH1A1KDM4E | |
| SCHEMBL21316428 | 0.67 | GPR35 (0.58) | MAOBMAOAHSD17B10GPR35ALDH1A1 | |
| SCHEMBL25167999 | 0.67 | AKR1B10 (0.43) | MAOBMAOAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL30422928 | 0.67 | AKR1B10 (0.43) | MAOBMAOAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL25168020 | 0.67 | AKR1B10 (0.43) | MAOBMAOAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL30423318 | 0.67 | AKR1B10 (0.43) | MAOBMAOAHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10399964-B2 | Coumarin-linked taxanes for detection and circumvention of cellular efflux | THE UNIVERSITY OF KANSAS (US) | 2019-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10399964-B2 | Coumarin-linked taxanes for detection and circumvention of cellular efflux | SLC6A1, ABCB11, SLC6A11 | MAOB 1947/4885NPC1 74/4885RAB9A 3941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.