Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 13/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761601 | 0.73 | TNKS (0.42) | TNKSPRMT5METTL3KITMETTL14 | |
| Hydrochloric Acid SCHEMBL1761591 | 0.72 | TNKS (0.42) | TNKSPRMT5METTL3KITMETTL14 | |
| SCHEMBL260898 | 0.71 | HTR3A (0.64) | — | |
| SCHEMBL261296 | 0.71 | HTR3A (0.64) | — | |
| SCHEMBL260289 | 0.71 | HTR3A (0.64) | — | |
| SCHEMBL24112335 | 0.71 | METTL3 (0.55) | METTL3KIT | |
| SCHEMBL459667 | 0.71 | METTL3 (0.52) | PRMT5METTL3KIT | |
| SCHEMBL8354196 | 0.70 | PARP1 (0.51) | TNKSPRMT5METTL3CNR2CNR1 | |
| SCHEMBL8357643 | 0.70 | PARP1 (0.51) | TNKSPRMT5METTL3CNR2CNR1 | |
| SCHEMBL2587386 | 0.68 | METTL3 (0.53) | PRMT5METTL3KITTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252811-B2 | Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2012-08-28 | — | — | US | disclosed |
| US-20120101094-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | XIE WENGE (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101094-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | CHRNA7, CHRNA5, CHRNA3 | TNKS 2468/4885PRMT5 1273/4885METTL3 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.