SCHEMBL213326

SCHEMBL213326

C[Si](C)(C)O/N=C/c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PLA2G7 Q13093 2/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
NOX1 Q9Y5S8 1/20 0.38
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
FAAH O00519 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
TAAR1 Q96RJ0 2/20 0.36
GRIN2D O15399 2/20 0.36
GRIN3B O60391 2/20 0.36
GRIN1 Q05586 2/20 0.36
GRIN2A Q12879 2/20 0.36
GRIN2B Q13224 2/20 0.36
GRIN2C Q14957 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL213327 1.00 LMNA (0.46) LMNAL3MBTL1PLA2G7MEN1KMT2A
SCHEMBL214984 0.81 LMNA (0.44) LMNAL3MBTL1PLA2G7MEN1KMT2A
SCHEMBL214983 0.81 LMNA (0.44) LMNAL3MBTL1PLA2G7MEN1KMT2A
SCHEMBL213104 0.76 PLA2G7 (0.50) LMNAL3MBTL1PLA2G7MEN1KMT2A
SCHEMBL213105 0.76 PLA2G7 (0.50) LMNAL3MBTL1PLA2G7MEN1KMT2A
SCHEMBL213106 0.76 PLA2G7 (0.50) LMNAL3MBTL1PLA2G7MEN1KMT2A
SCHEMBL17256939 0.75 ALDH1A1 (0.51) LMNAL3MBTL1MEN1KMT2ARAB9A
SCHEMBL17256937 0.75 ALDH1A1 (0.51) LMNAL3MBTL1MEN1KMT2ARAB9A
SCHEMBL113601 0.75 LMNA (0.52) LMNAL3MBTL1PLA2G7MEN1KMT2A
SCHEMBL113602 0.75 LMNA (0.52) LMNAL3MBTL1PLA2G7MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed