Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 2/20 | 0.55 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.55 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.55 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.53 |
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | GLI1 | P08151 | 1/20 | 0.48 |
| ▸ | GLI2 | P10070 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21332550 | 0.88 | MAPT (0.56) | EPHX2LTA4HMEN1KMT2ATAAR1 | |
| SCHEMBL21332514 | 0.88 | LTA4H (0.55) | EPHX2LTA4HPOLBNPC1RAB9A | |
| SCHEMBL21346281 | 0.88 | EPHX2 (0.55) | EPHX2NPC1RAB9AMAPTSLC5A1 | |
| SCHEMBL21332469 | 0.88 | SLC5A1 (0.61) | MEN1KMT2ATAAR1RAB9AMAPT | |
| SCHEMBL21333665 | 0.88 | LTA4H (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4EPHX2 | |
| SCHEMBL21332709 | 0.87 | RAB9A (0.46) | PLAAT3PLAAT5PLAAT2PLAAT4EPHX2 | |
| SCHEMBL21332561 | 0.87 | KMT2A (0.53) | PLAAT3PLAAT5PLAAT2PLAAT4MEN1 | |
| SCHEMBL21345898 | 0.86 | HPGD (0.58) | EPHX2GAASMN1; SMN2 | |
| SCHEMBL21332544 | 0.86 | LTA4H (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4EPHX2 | |
| SCHEMBL21332630 | 0.85 | SLC5A1 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-02-07 | — | — | US | disclosed |
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-02-07 | — | — | US | disclosed |
| US-20210017126-A1 | Antibacterial Agents: Arylalkylcarboxamido Phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2021-01-21 | — | — | US | disclosed |
| US-20210017126-A1 | Antibacterial Agents: Arylalkylcarboxamido Phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2021-01-21 | — | — | US | disclosed |
| WO-2019173507-A1 | ANTIBACTERIAL AGENTS : ARYLALKYLCARBOXAMIDO PHLOROGLUCINOLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-09-12 | — | — | WO | disclosed |
| WO-2019173507-A1 | ANTIBACTERIAL AGENTS : ARYLALKYLCARBOXAMIDO PHLOROGLUCINOLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RNGTT, FBL, POLR1C | PLAAT3 2861/4885PLAAT5 1873/4885PLAAT2 2093/4885 |
| US-20210017126-A1 | Antibacterial Agents: Arylalkylcarboxamido Phloroglucinols | RNGTT, FBL, POLR1C | PLAAT3 2861/4885PLAAT5 1873/4885PLAAT2 2093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.