Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21332569 | 0.94 | HIF1A (0.44) | RAB9AHDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL21332541 | 0.88 | EPHX1 (0.43) | RAB9ASMN1; SMN2EPHX2KMT2ACYP3A4 | |
| SCHEMBL21332630 | 0.88 | SLC5A1 (0.42) | SLC5A1SLC5A2EPHX2KMT2AALDH1A1 | |
| SCHEMBL21332561 | 0.87 | KMT2A (0.53) | RAB9AHDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL21332776 | 0.87 | PLAAT3 (0.55) | RAB9ASMN1; SMN2SLC5A1SLC5A2NPC1 | |
| SCHEMBL21332469 | 0.86 | SLC5A1 (0.61) | RAB9ASMN1; SMN2SLC5A1SLC5A2KMT2A | |
| SCHEMBL21332550 | 0.86 | MAPT (0.56) | RAB9ASMN1; SMN2NPC1EPHX2KMT2A | |
| SCHEMBL21346281 | 0.86 | EPHX2 (0.55) | RAB9ASMN1; SMN2SLC5A1SLC5A2NPC1 | |
| SCHEMBL21332514 | 0.86 | LTA4H (0.55) | RAB9ASMN1; SMN2SLC5A1SLC5A2NPC1 | |
| SCHEMBL21346280 | 0.85 | KMT2A (0.40) | HDAC2SLC5A1SLC5A2EPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-02-07 | — | — | US | disclosed |
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-02-07 | — | — | US | disclosed |
| US-20210017126-A1 | Antibacterial Agents: Arylalkylcarboxamido Phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2021-01-21 | — | — | US | disclosed |
| US-20210017126-A1 | Antibacterial Agents: Arylalkylcarboxamido Phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2021-01-21 | — | — | US | disclosed |
| WO-2019173507-A1 | ANTIBACTERIAL AGENTS : ARYLALKYLCARBOXAMIDO PHLOROGLUCINOLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-09-12 | — | — | WO | disclosed |
| WO-2019173507-A1 | ANTIBACTERIAL AGENTS : ARYLALKYLCARBOXAMIDO PHLOROGLUCINOLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RNGTT, FBL, POLR1C | RAB9A 4138/4885HDAC2 673/4885HDAC8 171/4885 |
| US-20210017126-A1 | Antibacterial Agents: Arylalkylcarboxamido Phloroglucinols | RNGTT, FBL, POLR1C | RAB9A 4138/4885HDAC2 673/4885HDAC8 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.