Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843650 | 0.85 | CYP1A2 (0.43) | ALDH1A1KMT2AENPP2SIGMAR1CHRM2 | |
| SCHEMBL8843644 | 0.85 | CYP1A2 (0.43) | ALDH1A1KMT2AENPP2SIGMAR1CHRM2 | |
| SCHEMBL4550640 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL6166891 | 0.82 | ENPP2 (0.48) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL7801189 | 0.80 | ENPP2 (0.55) | L3MBTL1ENPP2SIGMAR1CHRM2CHRM5 | |
| SCHEMBL633907 | 0.79 | SIGMAR1 (0.54) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL633302 | 0.79 | SIGMAR1 (0.54) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL190556 | 0.79 | ENPP2 (0.57) | ALDH1A1L3MBTL1ENPP2SIGMAR1 | |
| SCHEMBL22285161 | 0.79 | ENPP2 (0.57) | ALDH1A1L3MBTL1ENPP2SIGMAR1 | |
| SCHEMBL8381132 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101257-A1 | PROCESSES FOR PREPARING AMINO-SUBSTITUTED GAMMA-LACTAMS | UNIVERSITE DE MONTREAL (CA) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101257-A1 | PROCESSES FOR PREPARING AMINO-SUBSTITUTED GAMMA-LACTAMS | QPCT, GLUL, ASNS | ALDH1A1 3660/4885KMT2A 4277/4885MAPK1 4520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.