Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13067201 | 0.83 | LMNA (0.38) | ALDH1A1ATMSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL1520825 | 0.69 | RAB9A (0.78) | RAB9ASMN1; SMN2NPC1L3MBTL1HTT | |
| SCHEMBL844271 | 0.69 | MEN1 (0.48) | RAB9AALDH1A1ATMSMN1; SMN2NPC1 | |
| SCHEMBL21338287 | 0.69 | MEN1 (0.45) | RAB9AALDH1A1ATMSMN1; SMN2NPC1 | |
| SCHEMBL16998708 | 0.68 | ALDH1A1 (0.38) | RAB9AALDH1A1ATMSMN1; SMN2NPC1 | |
| SCHEMBL22304128 | 0.67 | P2RX7 (0.33) | — | |
| SCHEMBL27218809 | 0.65 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1LMNAL3MBTL1 | |
| SCHEMBL27218904 | 0.65 | LOXL2 (0.47) | RAB9ASMN1; SMN2NPC1LMNAHPGD | |
| SCHEMBL844198 | 0.65 | MEN1 (0.53) | RAB9AALDH1A1ATMSMN1; SMN2NPC1 | |
| SCHEMBL8018804 | 0.64 | KMT2A (0.49) | RAB9AALDH1A1LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432776-B1 | METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | UNIV LAVAL (CA) | 2019-09-11 | — | — | EP | disclosed |