SCHEMBL21339772

SCHEMBL21339772

CC(=O)N1CCCC1C(=O)NC(CCC(=O)OCc1ccccc1)C(=O)NCCN

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ ALDH1A1 P00352 1/20 0.52
▸ HPGD P15428 1/20 0.52
▸ BCHE P06276 2/20 0.50
▸ ACHE P22303 2/20 0.50
▸ CACNA1F O60840 1/20 0.50
▸ CACNA1D Q01668 1/20 0.50
▸ CACNA1S Q13698 1/20 0.50
▸ CACNA1C Q13936 1/20 0.50
▸ CTRB1 P17538 1/20 0.47
▸ PRCP P42785 1/20 0.46
▸ CMA1 P23946 1/20 0.44
▸ REN P00797 1/20 0.44
▸ F2 P00734 2/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21166959 0.94 MEN1 (0.53) KMT2AMEN1ALDH1A1HPGDBCHE
SCHEMBL24801680 0.88 CTRB1 (0.46) KMT2AMEN1ALDH1A1HPGDCTRB1
SCHEMBL21346666 0.84 REN (0.54) RENACE
SCHEMBL21350914 0.84 ITGB1 (0.42) RENF2CPA1CPA2CPA4
SCHEMBL21339802 0.84 APLNR (0.40) KMT2AALDH1A1RENF2TSHR
SCHEMBL21166989 0.82 ACE (0.45) RENF2CPA1CPA2CPA4
SCHEMBL21166966 0.80 ITGB1 (0.44) RENF2ACEITGB1ITGA4
SCHEMBL21166986 0.79 ITGB3 (0.41) KMT2AMEN1CMA1RENF2
SCHEMBL21339619 0.79 ACE (0.40) KMT2AMEN1ALDH1A1HPGDBCHE
SCHEMBL23934950 0.78 MEN1 (0.61) KMT2AMEN1ALDH1A1HPGDBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11633460-B2 Injectable solution at pH 7 comprising at least one basal insulin wherein the pI is comprised from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals ADOCIA (FR) 2023-04-25 — — US disclosed
US-20190275115-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHEREIN THE PI IS COMPRISED FORM 5.8 TO 8.5 AND A CO-POLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS ADOCIA (FR) 2019-09-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11633460-B2 Injectable solution at pH 7 comprising at least one basal insulin wherein the pI is comprised from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals IAPP, HBB, IGF1R KMT2A 3929/4885MEN1 1193/4885ALDH1A1 4026/4885
US-20190275115-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHEREIN THE PI IS COMPRISED FORM 5.8 TO 8.5 AND A CO-POLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS IAPP, GCG, HBB KMT2A 3332/4885MEN1 1461/4885ALDH1A1 3585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback