SCHEMBL21343382

SCHEMBL21343382

CC1(C)c2ccccc2-c2c1ccc1oc3ccccc3c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
GLA P06280 1/20 0.35
CYP3A4 P08684 1/20 0.35
PGAM1 P18669 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALK Q9UM73 1/20 0.34
NTRK1 P04629 1/20 0.33
PLK3 Q9H4B4 1/20 0.33
PGR P06401 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19109365 0.93 TDP1 (0.35) MAOAKDM4EALDH1A1MAPTHPGD
SCHEMBL24519957 0.90 KDM4E (0.36) MAOAKDM4EALDH1A1MAPTHPGD
SCHEMBL24518898 0.88 ALOX5 (0.33) MEN1KMT2APGR
SCHEMBL24519001 0.88 HSP90AA1 (0.34) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL20205330 0.88 KDM4E (0.38) MAOAKDM4EALDH1A1MAPTHPGD
SCHEMBL24518895 0.87 HCRTR1 (0.34) MAOAKDM4EALDH1A1MAPTHPGD
SCHEMBL24518910 0.86 WEE1 (0.35) ALKWEE1L3MBTL1AHR
SCHEMBL24518896 0.85 HCRTR1 (0.33) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL24519111 0.85 HCRTR1 (0.31) WEE1
SCHEMBL24870958 0.84 CDC25A (0.36) MAOAKDM4EALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230276706-A1 NOVEL HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DIODE INCLUDING SAME SFC CO., LTD. (KR) 2023-08-31 US disclosed
US-20230276706-A1 NOVEL HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DIODE INCLUDING SAME SFC CO., LTD. (KR) 2023-08-31 US disclosed
EP-4190771-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC Co., Ltd. (KR) 2023-06-07 EP disclosed
US-20220209132-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Changchun Hyperions Technology Co., Ltd. (CN) 2022-06-30 US disclosed
EP-4019503-A2 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Changchun Hyperions Technology Co., Ltd. (CN) 2022-06-29 EP disclosed
US-20210005821-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-01-07 US disclosed
US-20200227644-A1 ORGANIC LIGHT-EMITTING DIODE OPERABLE AT LOW VOLTAGE WITH HIGH EFFICIENCY AND LONG LIFETIME SFC CO., LTD. (KR) 2020-07-16 US disclosed
EP-3660934-A1 ORGANIC LIGHT EMITTING ELEMENT CAPABLE OF DRIVING AT LOW VOLTAGE AND HAVING HIGH EFFICIENCY AND LONG LIFE CHARACTERISTICS SFC Co., Ltd. (KR) 2020-06-03 EP disclosed
WO-2019170572-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-12 WO disclosed
WO-2019170578-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276706-A1 NOVEL HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DIODE INCLUDING SAME CYBA, CYP1B1, PPOX MAOA 248/4885KDM4E 4031/4885ALDH1A1 30/4885
US-20210005821-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM MAOA 582/4885KDM4E 3061/4885ALDH1A1 33/4885
US-20220209132-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME EML4, STOM, GJB2 MAOA 78/4885KDM4E 1381/4885ALDH1A1 2548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.