SCHEMBL21351815

SCHEMBL21351815

CCS(=O)(=O)N1c2ccccc2CC1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACE P12821 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21351819 0.87 ALDH1A1 (0.43) ACE
SCHEMBL5847437 0.85 ACE (0.49) ACE
SCHEMBL5847471 0.85 ACE (0.49) ACE
SCHEMBL5847440 0.85 ACE (0.49) ACE
SCHEMBL21351810 0.85 DRD2 (0.46)
SCHEMBL21183355 0.81 ACE (0.45) ACE
SCHEMBL28751377 0.81 LMNA (0.52) ACE
SCHEMBL22566241 0.79 MMP8 (0.49) ACE
SCHEMBL23351448 0.78 LMNA (0.60)
SCHEMBL15280427 0.78 LMNA (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109906221-B N-alkylsulfonylindoline compound, agricultural and horticultural insecticide containing the same, and method of using the same 日本农药株式会社 2021-10-01 CN disclosed
US-10716306-B2 N-alkylsulfonyl indoline compound, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide NIHON NOHYAKU CO., LTD. (JP) 2020-07-21 US disclosed
US-20200077659-A1 N-ALKYLSULFONYL INDOLINE COMPOUND, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE NIHON NOHYAKU CO., LTD. (JP) 2020-03-12 US disclosed
EP-3539958-A1 N-ALKYLSULFONYLINDOLINE COMPOUND, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING SAME AND METHOD FOR USE THEREOF Nihon Nohyaku Co., Ltd. (JP) 2019-09-18 EP disclosed
CN-109906221-A N- alkyl sulphonyl sulfonylindoline compounds and salt, garderning pesticide and its application method containing the compound 日本农药株式会社 2019-06-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200077659-A1 N-ALKYLSULFONYL INDOLINE COMPOUND, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE INMT, AS3MT, HACL2 ACE 494/4885
US-10716306-B2 N-alkylsulfonyl indoline compound, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide INMT, AS3MT, HACL2 ACE 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.