SCHEMBL21361137

SCHEMBL21361137

Cc1cc(C#N)c2ncn(-c3ccccc3)c2c1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 6/20 0.49
▸ SRC P12931 4/20 0.46
▸ HTT P42858 2/20 0.41
▸ ALDH1A1 P00352 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ MAPK10 P53779 1/20 0.40
▸ NCOA1 Q15788 1/20 0.40
▸ NCOA3 Q9Y6Q9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24844368 0.81 FGFR1 (0.40) FGFR1SRCHTTALDH1A1
SCHEMBL17940706 0.80 HTT (0.51) FGFR1SRCHTT
SCHEMBL17940746 0.78 HPGD (0.41) FGFR1SRCALDH1A1HPGD
SCHEMBL17940747 0.77 HPGD (0.48) FGFR1ALDH1A1HPGD
SCHEMBL17940732 0.73 GABRA1 (0.49) FGFR1SRCHTTALDH1A1
SCHEMBL29642847 0.73 GABRA1 (0.49) FGFR1SRCHTTALDH1A1
SCHEMBL17940725 0.73 FGFR1 (0.59) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL17940689 0.71 CYP17A1 (0.39) FGFR1SRCMAPK1
SCHEMBL17940726 0.70 HCAR1 (0.41) FGFR1ALDH1A1HPGDMAPK1
SCHEMBL13993884 0.69 FGFR1 (0.76) FGFR1SRCHTTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10418569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10418569-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP2 FGFR1 2889/4885SRC 1034/4885HTT 2766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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