Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719727 | 0.92 | DRD2 (0.56) | DRD2DRD4ALDH1A1L3MBTL1HTR1A | |
| SCHEMBL7803381 | 0.85 | L3MBTL1 (0.66) | DRD2DRD4ALDH1A1L3MBTL1HTR1A | |
| SCHEMBL30407538 | 0.85 | ALDH1A1 (0.55) | DRD2DRD4ALDH1A1L3MBTL1HTR1A | |
| SCHEMBL21361478 | 0.81 | DRD2 (0.49) | DRD2DRD4ALDH1A1L3MBTL1HTR1A | |
| SCHEMBL10819392 | 0.81 | DRD2 (0.58) | DRD2DRD4ALDH1A1HTR1AKMT2A | |
| SCHEMBL30952473 | 0.81 | HTR3A (0.66) | DRD2HTR1ADRD3 | |
| SCHEMBL2875715 | 0.81 | HTR3A (0.66) | DRD2HTR1ADRD3 | |
| SCHEMBL11150752 | 0.80 | DRD2 (0.71) | DRD2ALDH1A1L3MBTL1HTR1AGFER | |
| Hydrochloric Acid SCHEMBL5988519 | 0.79 | LMNA (0.67) | DRD2HTR1ADRD3 | |
| Hydrochloric Acid SCHEMBL7834101 | 0.79 | LMNA (0.67) | DRD2HTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178510-A1 | TRIAZACYCLODODECANSULFONAMIDE (\"TCD\")-BASED PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-09-19 | — | — | WO | disclosed |