Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21361554 | 0.71 | HPGD (0.46) | DPP7HTT | |
| SCHEMBL5120051 | 0.67 | SIGMAR1 (0.53) | DPP7HRH3 | |
| SCHEMBL7200272 | 0.64 | APP (0.48) | HTTHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL465332 | 0.64 | ACKR3 (0.52) | HTTHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL24196895 | 0.64 | PRMT6 (0.51) | — | |
| SCHEMBL1239442 | 0.64 | L3MBTL1 (0.55) | HTTHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11795941 | 0.63 | HDAC3 (0.56) | HTTHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4974601 | 0.63 | HDAC3 (0.61) | HTTHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7205397 | 0.63 | REN (0.49) | — | |
| SCHEMBL13215087 | 0.63 | HDAC3 (0.46) | HDAC3HDAC1HDAC2HDAC8NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178510-A1 | TRIAZACYCLODODECANSULFONAMIDE (\"TCD\")-BASED PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-09-19 | — | — | WO | disclosed |