Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | IAPP | P10997 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1320673 | 0.84 | IAPP (0.47) | IAPPKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8676074 | 0.84 | IAPP (0.47) | IAPPKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11130587 | 0.84 | ALDH1A1 (0.53) | IAPPKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1320671 | 0.84 | IAPP (0.47) | IAPPKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11130591 | 0.84 | ALDH1A1 (0.53) | IAPPKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5678522 | 0.83 | ALDH1A1 (0.47) | AKR1C3AKR1C2AKR1C1KDM4EALDH1A1 | |
| SCHEMBL5678519 | 0.83 | ALDH1A1 (0.47) | AKR1C3AKR1C2AKR1C1KDM4EALDH1A1 | |
| SCHEMBL7052252 | 0.83 | IAPP (0.47) | AKR1C3AKR1C2AKR1C1IAPPKDM4E | |
| SCHEMBL7052246 | 0.83 | IAPP (0.47) | AKR1C3AKR1C2AKR1C1IAPPKDM4E | |
| SCHEMBL6924559 | 0.82 | ALDH1A1 (0.43) | AKR1C3AKR1C2AKR1C1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190282478-A1 | ANTIMICROBIAL COMPOSITIONS | SYMRISE AG (DE) | 2019-09-19 | — | — | US | disclosed |
| CN-1638718-A | Additives and products including oligoesters | CRODA INC (US) | 2005-07-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190282478-A1 | ANTIMICROBIAL COMPOSITIONS | MPO, NHERF1, NOX1 | AKR1C3 2488/4885AKR1C2 3000/4885AKR1C1 2811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.