Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 5/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.32 |
| ▸ | LPL | P06858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362596 | 0.84 | LPL (0.42) | CXCR2LIPGLPLALDH1A1LMNA | |
| SCHEMBL20157831 | 0.81 | CXCR2 (0.40) | CXCR2THRBLIPGLPLMAPT | |
| SCHEMBL20157880 | 0.81 | CXCR2 (0.36) | CXCR2THRBLIPGLPLMAPT | |
| SCHEMBL20157420 | 0.79 | CXCR2 (0.36) | CXCR2THRBLIPGLPLMAPT | |
| SCHEMBL20157565 | 0.79 | LMNA (0.43) | CXCR2THRBLIPGLPLMAPT | |
| SCHEMBL20157558 | 0.78 | CXCR2 (0.37) | CXCR2THRBLIPGLPLMAPT | |
| SCHEMBL20157904 | 0.78 | CXCR2 (0.35) | CXCR2THRBLIPGLPLMAPT | |
| SCHEMBL21362081 | 0.77 | CXCR2 (0.38) | CXCR2THRBLIPGLPLMAPT | |
| SCHEMBL21362027 | 0.76 | CXCR2 (0.35) | CXCR2THRBLIPGLPLMAPT | |
| SCHEMBL20157902 | 0.75 | CXCR2 (0.41) | CXCR2THRBLIPGLPLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |