Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.57 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848490 | 0.88 | PKM (0.54) | MAPTMEN1KMT2AGPR84AHR | |
| SCHEMBL21366214 | 0.82 | MAPT (0.70) | MAPTMEN1KMT2AGPR84AHR | |
| SCHEMBL21366219 | 0.81 | MEN1 (0.65) | MAPTMEN1KMT2AGPR84AHR | |
| SCHEMBL21448958 | 0.79 | MAPT (0.66) | MAPTMEN1KMT2AGPR84AHR | |
| SCHEMBL21448917 | 0.78 | MAPT (0.65) | MAPTMEN1KMT2AGPR84AHR | |
| SCHEMBL21448959 | 0.78 | MAPT (0.65) | MAPTMEN1KMT2AGPR84AHR | |
| SCHEMBL21366220 | 0.78 | MAPT (0.65) | MAPTMEN1KMT2AGPR84AHR | |
| SCHEMBL21448916 | 0.78 | MEN1 (0.65) | MAPTMEN1KMT2AGPR84AHR | |
| SCHEMBL23551150 | 0.78 | GPR84 (0.54) | MAPTMEN1KMT2AGPR84AHR | |
| SCHEMBL29567209 | 0.77 | MEN1 (1.00) | MAPTMEN1KMT2AGPR84AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564239-B9 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN INC (US) | 2023-04-19 | — | — | EP | disclosed |
| US-20230054194-A1 | Methods of Treating Cancer | ARIAGEN, INC. (US) | 2023-02-23 | — | — | US | disclosed |
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | ARIAGEN, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-11459322-B2 | Indole compounds and their use | ARIAGEN, INC. (US) | 2022-10-04 | — | — | US | disclosed |
| US-20210179604-A1 | Indole Compounds and Their Use | ARIAGEN, INC. (US) | 2021-06-17 | — | — | US | disclosed |
| US-20200354353-A1 | Indole Compounds and Their Use | ARIAGEN, INC. (US) | 2020-11-12 | — | — | US | disclosed |
| EP-3564239-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | Shenzhen Immunova Pharmaceutical Co., Ltd. (CN) | 2019-11-06 | — | — | EP | disclosed |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR PHARMACEUTICALS, INC. | 2019-10-31 | — | — | US | disclosed |
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-10-10 | — | — | US | disclosed |
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | ARIAGEN, INC. (US) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190307731-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | MAPT 4875/4885MEN1 4131/4885KMT2A 1490/4885 |
| US-11547698-B2 | Aryl hydrocarbon receptor modulators | AHR, ARNT, CNR1 | MAPT 4838/4885MEN1 4176/4885KMT2A 1471/4885 |
| US-20210179604-A1 | Indole Compounds and Their Use | IDO1, IDO2, INMT | MAPT 2556/4885MEN1 2883/4885KMT2A 1124/4885 |
| US-11459322-B2 | Indole compounds and their use | IDO1, IDO2, INMT | MAPT 2556/4885MEN1 2883/4885KMT2A 1124/4885 |
| US-20200354353-A1 | Indole Compounds and Their Use | IDO1, IDO2, INMT | MAPT 2556/4885MEN1 2883/4885KMT2A 1124/4885 |
| US-20190284149-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | AHR, ARNT, NR1H4 | MAPT 4863/4885MEN1 4131/4885KMT2A 1445/4885 |
| US-20190330201-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS | AHR, ARNT, CNR1 | MAPT 4838/4885MEN1 4176/4885KMT2A 1471/4885 |
| US-20230054194-A1 | Methods of Treating Cancer | TP53, MSH2, PDCD1 | MAPT 3515/4885MEN1 1911/4885KMT2A 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.