Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27485197 | 0.70 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL12035184 | 0.68 | LMNA (0.34) | — | |
| SCHEMBL28313631 | 0.67 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL23007075 | 0.65 | NFKB1 (0.38) | MAPK1 | |
| SCHEMBL29054770 | 0.62 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL20224875 | 0.62 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL29797163 | 0.62 | RECQL (0.34) | MAPK1 | |
| SCHEMBL151606 | 0.62 | RECQL (0.34) | MAPK1 | |
| SCHEMBL7849903 | 0.62 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL29769053 | 0.61 | MAPK1 (0.32) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019177873-A1 | ARGINASE INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2019-09-19 | — | — | WO | disclosed |