Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663796 | 0.79 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL27485197 | 0.73 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL21367073 | 0.67 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL29054770 | 0.64 | MAPK1 (0.39) | MAPK1RECQL | |
| SCHEMBL29769053 | 0.63 | MAPK1 (0.32) | MAPK1RECQL | |
| SCHEMBL21469716 | 0.61 | — | — | |
| SCHEMBL20766890 | 0.61 | MAPK1 (0.36) | MAPK1 | |
| SCHEMBL746387 | 0.61 | EGLN1 (0.52) | MAPK1 | |
| SCHEMBL7477725 | 0.60 | GABRA1 (0.33) | — | |
| SCHEMBL23007075 | 0.60 | NFKB1 (0.38) | MAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881661-A | Condensed heterocyclic derivative | 杨森科学爱尔兰无限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117715909-A | Condensed heterocyclic derivative | 杨森科学爱尔兰无限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117597336-A | Halogen substituted amino aza-heteroaryl compounds as inhibitors of hematopoietic progenitor kinase 1 (HPK 1) | 安大略省癌症研究所(OICR) | 2024-02-23 | — | — | CN | disclosed |
| CN-116744927-A | Fused heterocyclic derivatives and their use in the treatment of HBV infection | 杨森科学爱尔兰无限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-115968372-A | Radioprotective and chemoprotective compounds | 通尼克斯医药有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-109195965-B | Inhibitors of WDR5 protein-protein binding | 普罗佩纶治疗公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-112638381-A | Muscarinic acetylcholine M1 receptor antagonists | 帕珀莱恩医疗公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |