Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27852153 | 0.83 | TDP1 (0.66) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| Benzyl Salicylate SCHEMBL1871397 | 0.82 | TDP1 (1.00) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| Benzyl Salicylate SCHEMBL15573 | 0.82 | TDP1 (1.00) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| Benzyl Salicylate SCHEMBL30184766 | 0.82 | TDP1 (1.00) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL2704242 | 0.81 | ALDH1A1 (0.53) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL22192829 | 0.81 | ALDH1A1 (0.54) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL13595553 | 0.81 | CES2 (0.55) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| Benzyl Salicylate SCHEMBL27731147 | 0.81 | TDP1 (0.96) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| Benzyl Salicylate SCHEMBL7199160 | 0.81 | TDP1 (0.96) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL25552709 | 0.80 | ALDH1A1 (0.50) | TDP1ALDH1A1MAPK1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230135635-A1 | INHIBITORS OF ULK1/2 AND METHODS OF USING SAME | Sanford Burnham Prebys Medical Discovery Institute | 2023-05-04 | — | — | US | disclosed |
| US-20230135635-A1 | INHIBITORS OF ULK1/2 AND METHODS OF USING SAME | Sanford Burnham Prebys Medical Discovery Institute | 2023-05-04 | — | — | US | disclosed |
| WO-2021163629-A1 | INHIBITORS OF ULK1/2 AND METHODS OF USING SAME | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-08-19 | — | — | WO | disclosed |
| US-20190284371-A1 | FUNCTIONALIZED ORGANOSULFUR COMPOUND FOR REDUCING HYSTERESIS IN A RUBBER ARTICLE | SI GROUP, INC. | 2019-09-19 | — | — | US | disclosed |
| WO-2019178373-A1 | PHENOLIC RESIN COMPOSITION AND THE USE THEREOF IN A RUBBER COMPOSITION TO REDUCE HYSTERESIS | SI GROUP, INC. (US) | 2019-09-19 | — | — | WO | disclosed |
| WO-2019178381-A1 | FUNCTIONALIZED ORGANOSULFUR COMPOUND FOR REDUCING HYSTERESIS IN A RUBBER ARTICLE | SI GROUP, INC. (US) | 2019-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230135635-A1 | INHIBITORS OF ULK1/2 AND METHODS OF USING SAME | ULK2, ULK1, ULK3 | TDP1 607/4885ALDH1A1 4012/4885MAPK1 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.