Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.45 |
| ▸ | MASP2 | O00187 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21358724 | 0.87 | POLB (0.54) | ALDH1A1POLB | |
| SCHEMBL21358725 | 0.87 | POLB (0.54) | ALDH1A1POLB | |
| SCHEMBL21376628 | 0.82 | ITGB1 (0.49) | OPRM1OPRL1FOLH1SLC2A1GAA | |
| SCHEMBL21376456 | 0.80 | ACE (0.47) | FOLH1ALDH1A1LMNAPOLB | |
| SCHEMBL21376447 | 0.80 | ALDH1A1 (0.64) | FOLH1GAAEPHX2ALDH1A1 | |
| SCHEMBL21376455 | 0.79 | PPID (0.47) | ALDH1A1LMNAPOLB | |
| SCHEMBL21376642 | 0.78 | ITGA4 (0.50) | OPRM1OPRL1FOLH1SLC2A1GAA | |
| Lozilurea SCHEMBL1812194 | 0.78 | GAA (0.56) | OPRM1OPRL1SLC2A1GAAEPHX2 | |
| SCHEMBL21376443 | 0.77 | PPARG (0.54) | EPHX2ALDH1A1POLB | |
| SCHEMBL21376639 | 0.76 | OPRM1 (0.43) | OPRM1OPRL1FOLH1SLC2A1MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178248-A1 | INHIBITORS OF INTEGRIN ALPHA 2 BETA 1 AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-19 | — | — | WO | disclosed |