Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.47 |
| ▸ | MME | P08473 | 4/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21358724 | 0.90 | POLB (0.54) | ALDH1A1POLBPPARGSMN1; SMN2ITGB1 | |
| SCHEMBL21358725 | 0.90 | POLB (0.54) | ALDH1A1POLBPPARGSMN1; SMN2ITGB1 | |
| SCHEMBL21376455 | 0.89 | PPID (0.47) | ALDH1A1LMNACA1CA2CA7 | |
| SCHEMBL21376443 | 0.87 | PPARG (0.54) | ACEALDH1A1POLBPPARGSMN1; SMN2 | |
| SCHEMBL21376446 | 0.80 | OPRM1 (0.52) | ALDH1A1LMNAPOLBFOLH1 | |
| SCHEMBL21376447 | 0.77 | ALDH1A1 (0.64) | ALDH1A1FOLH1SMN1; SMN2 | |
| SCHEMBL21376631 | 0.76 | ITGB1 (0.50) | ALDH1A1LMNAITGB1ITGA2 | |
| SCHEMBL21376627 | 0.74 | ITGA4 (0.56) | ALDH1A1LMNAITGB1 | |
| SCHEMBL24575913 | 0.72 | MEN1 (0.65) | ALDH1A1CA2SMN1; SMN2 | |
| SCHEMBL11570507 | 0.71 | NAALAD2 (0.66) | ACEMMECPA1ACE2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178248-A1 | INHIBITORS OF INTEGRIN ALPHA 2 BETA 1 AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-19 | — | — | WO | disclosed |