Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376790 | 0.86 | MEN1 (0.38) | MAPTLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL665103 | 0.82 | RORC (0.59) | MAPTLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29978121 | 0.82 | RORC (0.59) | MAPTLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL21376808 | 0.75 | RAB9A (0.54) | MAPTLMNAALDH1A1MAPK1RAB9A | |
| SCHEMBL28558981 | 0.74 | MEN1 (0.47) | MAPTLMNAALDH1A1MAPK1RAB9A | |
| SCHEMBL21376607 | 0.73 | MEN1 (0.37) | MAPTLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL664968 | 0.73 | L3MBTL1 (0.60) | MAPTLMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL29977930 | 0.73 | L3MBTL1 (0.60) | MAPTLMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL21376507 | 0.73 | SMN1; SMN2 (0.62) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21376321 | 0.73 | MAPT (0.52) | MAPTRAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |