Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376583 | 0.86 | MAPT (0.41) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL21376607 | 0.80 | MEN1 (0.37) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL664968 | 0.80 | L3MBTL1 (0.60) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL29977930 | 0.80 | L3MBTL1 (0.60) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL21376928 | 0.75 | L3MBTL1 (0.61) | MAPTALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL665103 | 0.73 | RORC (0.59) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL29978121 | 0.73 | RORC (0.59) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL21376803 | 0.72 | RXFP1 (0.56) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL21376808 | 0.71 | RAB9A (0.54) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL21376787 | 0.71 | AKR1C3 (0.53) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |