Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HHAT | Q5VTY9 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509163 | 0.90 | MTNR1B (0.51) | MTNR1BACEDRD1MEN1RECQL | |
| SCHEMBL9508502 | 0.87 | MTNR1B (0.57) | MTNR1BACEDRD1OPRD1OPRM1 | |
| SCHEMBL9508492 | 0.83 | MTNR1B (0.41) | MTNR1BACE | |
| SCHEMBL12527605 | 0.82 | MTNR1B (0.56) | MTNR1BACEDRD1OPRD1OPRM1 | |
| SCHEMBL2138396 | 0.82 | DRD1 (0.59) | MTNR1BACEDRD1NPSR1HHAT | |
| SCHEMBL9508177 | 0.80 | ACE (0.49) | MTNR1BACEDRD1NPSR1HHAT | |
| SCHEMBL9511054 | 0.78 | ACE (0.45) | MTNR1BACEDRD1NPSR1HHAT | |
| SCHEMBL10770517 | 0.78 | ACE (0.48) | MTNR1BACEDRD1NPSR1HHAT | |
| SCHEMBL22461287 | 0.78 | MTNR1B (0.50) | MTNR1BACEDRD1OPRD1OPRM1 | |
| SCHEMBL9511217 | 0.77 | OPRD1 (0.42) | MTNR1BACEDRD1OPRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230871-B1 | HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES | Monsanto Company (US) | 1993-09-22 | — | — | EP | claimed |
| EP-0236268-A1 | Plant protection by means of N-halogenoacetyl isoquinolines against herbicidal halogen acetanilides | CIBA-GEIGY AG (CH) | 1987-09-09 | — | — | EP | claimed |
| EP-0230871-A2 | Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | Monsanto Company (US) | 1987-08-05 | — | — | EP | claimed |
| EP-0230871-B1 | HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES | Monsanto Company (US) | 1993-09-22 | — | — | EP | disclosed |
| US-4755218-A | Reducing acetochlor injury to corn by applying with antidote | MONSANTO COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| EP-0236268-A1 | Plant protection by means of N-halogenoacetyl isoquinolines against herbicidal halogen acetanilides | CIBA-GEIGY AG (CH) | 1987-09-09 | — | — | EP | disclosed |