Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 5/20 | 0.35 |
| ▸ | FNTA | P49354 | 3/20 | 0.35 |
| ▸ | FNTB | P49356 | 3/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25468853 | 0.77 | RNPEP (0.34) | FNTAFNTB | |
| SCHEMBL173035 | 0.75 | PLA2G2C (0.42) | FOLH1PMP22 | |
| SCHEMBL24486692 | 0.75 | PLA2G2C (0.42) | FOLH1PMP22 | |
| SCHEMBL24701329 | 0.75 | ALDH1A1 (0.45) | FAAHFNTAFNTBPGGT1BMEN1 | |
| SCHEMBL17813082 | 0.74 | PLA2G2C (0.46) | FAAHMEN1KMT2APTPN1ALDH1A1 | |
| SCHEMBL6275580 | 0.73 | RNPEP (0.42) | FOLH1KDM4EALDH1A1 | |
| SCHEMBL5848394 | 0.73 | RNPEP (0.42) | FOLH1KDM4EALDH1A1 | |
| SCHEMBL20179249 | 0.73 | CTSK (0.35) | FOLH1FNTAFNTBPGGT1B | |
| SCHEMBL22133786 | 0.72 | ADRA1A (0.47) | FOLH1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL29768873 | 0.72 | FOLH1 (0.33) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3542821-A1 | p53 DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | Tokyo University of Science Foundation (JP) | 2019-09-25 | — | — | EP | disclosed |