Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.60 |
| ▸ | CES1 | P23141 | 9/20 | 0.58 |
| ▸ | CES2 | O00748 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28124342 | 0.98 | FAAH (0.61) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL14546387 | 0.98 | FAAH (0.61) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL15967394 | 0.98 | FAAH (0.61) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28442965 | 0.98 | FAAH (0.61) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL11232114 | 0.92 | CES1 (0.50) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL1548286 | 0.83 | FAAH (0.61) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL18584255 | 0.83 | FAAH (0.61) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL3631010 | 0.82 | FAAH (0.62) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL13975763 | 0.82 | FAAH (0.46) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL17835060 | 0.82 | CASP2 (0.62) | FAAHMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9341745-B2 | 3D network-structured silicon-containing prepolymer and method for fabricating the same | UNICON OPTICAL CO., LTD. (TW) | 2016-05-17 | — | — | US | claimed |
| US-20150309212-A1 | 3D NETWORK-STRUCTURED SILICON-CONTAINING PREPOLYMER AND METHOD FOR FABRICATING THE SAME | UNICON OPTICAL CO., LTD. (TW) | 2015-10-29 | — | — | US | claimed |
| US-20150252194-A1 | 3D NETWORK-STRUCTURED SILICON-CONTAINING PREPLOYMER AND METHOD FOR FABRICATING THE SAME | UNICON OPTICAL CO., LTD. (TW) | 2015-09-10 | — | — | US | claimed |
| CN-105440226-B | Silicon-containing hydrogel contact lens and manufacturing method of silicon-containing hydrogel | 望隼科技股份有限公司 | 2017-10-27 | — | — | CN | disclosed |
| US-9708450-B2 | Silicone hydrogel contact lens and method for manufacturing the same | VIZIONFOCUS INC. (TW) | 2017-07-18 | — | — | US | disclosed |
| US-9341745-B2 | 3D network-structured silicon-containing prepolymer and method for fabricating the same | UNICON OPTICAL CO., LTD. (TW) | 2016-05-17 | — | — | US | disclosed |
| CN-105440226-A | Silicon-containing hydrogel contact lens and manufacturing method of silicon-containing hydrogel | WANGSUN TECH CO LTD | 2016-03-30 | — | — | CN | disclosed |
| US-20160046801-A1 | SILICONE HYDROGEL CONTACT LENS AND METHOD FOR MANUFACTURING THE SAME | VIZIONFOCUS INC. (TW) | 2016-02-18 | — | — | US | disclosed |
| US-20150309212-A1 | 3D NETWORK-STRUCTURED SILICON-CONTAINING PREPOLYMER AND METHOD FOR FABRICATING THE SAME | UNICON OPTICAL CO., LTD. (TW) | 2015-10-29 | — | — | US | disclosed |
| US-20150252194-A1 | 3D NETWORK-STRUCTURED SILICON-CONTAINING PREPLOYMER AND METHOD FOR FABRICATING THE SAME | UNICON OPTICAL CO., LTD. (TW) | 2015-09-10 | — | — | US | disclosed |
| CN-103254436-B | Siliceous prepolymer and the siliceous glue using it obtained and contact lens | RISE TECHNOLOGY CO., LTD. (WS) | 2015-09-09 | — | — | CN | disclosed |
| CN-103254436-A | Silicious prepolymer, and silicious hydrogel and contact lens prepared through using it | Rise technology co ltd | 2013-08-21 | — | — | CN | disclosed |
| EP-2077292-B1 | Polysiloxane-based prepolymer and hydrogel | FAR EASTERN NEW CENTURY CORP (TW) | 2013-08-14 | — | — | EP | disclosed |
| EP-2508550-A1 | Novel silicon-containing contact lenses | Rise Technology Co., Ltd (WS) | 2012-10-10 | — | — | EP | disclosed |
| CN-101469068-B | Prepolymer containing silicon and silicon-containing glue and contact lens prepared therefrom | FAR EASTERN APPAREL CO LTD | 2011-09-21 | — | — | CN | disclosed |
| US-7906563-B2 | Polysiloxane-based prepolymer and hydrogel | FAR EASTERN NEW CENTURY CORPORATION (TW) | 2011-03-15 | — | — | US | disclosed |
| EP-2077292-A1 | Polysiloxane-based prepolymer and hydrogel | Far Eastern Texile Ltd. (CN) | 2009-07-08 | — | — | EP | disclosed |
| US-20090170976-A1 | Polysiloxane-based prepolymer and hydrogel | FAR EASTERN TEXTILE LTD. | 2009-07-02 | — | — | US | disclosed |
| CN-101469068-A | Prepolymer containing silicon and silicon-containing glue and contact lens prepared therefrom | FAR EASTERN APPAREL CO LTD (CN) | 2009-07-01 | — | — | CN | disclosed |
| EP-0459281-A2 | Method for making a microencapsulated liquid crystal | MERCK PATENT GmbH (DE) | 1991-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150309212-A1 | 3D NETWORK-STRUCTURED SILICON-CONTAINING PREPOLYMER AND METHOD FOR FABRICATING THE SAME | IL33, SMC3, HTR3D | FAAH 2461/4885CES1 2844/4885CES2 3006/4885 |
| US-20150252194-A1 | 3D NETWORK-STRUCTURED SILICON-CONTAINING PREPLOYMER AND METHOD FOR FABRICATING THE SAME | TAOK3, SMC3, HAO2 | FAAH 3790/4885CES1 2639/4885CES2 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.