Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389135 | 0.83 | — | — | |
| SCHEMBL21389132 | 0.78 | PER2 (0.40) | MEN1KMT2AATMKDM4ELMNA | |
| SCHEMBL22744722 | 0.74 | GRIN1 (0.34) | — | |
| SCHEMBL21389411 | 0.71 | PER2 (0.43) | MEN1KMT2AATMKDM4ELMNA | |
| SCHEMBL3546635 | 0.68 | CACNA1H (0.39) | MEN1KMT2AKDM4ELMNATP53 | |
| SCHEMBL26092846 | 0.65 | USP30 (0.50) | MEN1KMT2AMAPT | |
| SCHEMBL2312275 | 0.63 | ADRA1B (0.42) | MEN1KMT2AATMOPRM1OPRD1 | |
| SCHEMBL24060971 | 0.62 | TSHR (0.30) | — | |
| SCHEMBL26091546 | 0.62 | RIPK1 (0.43) | OPRM1OPRL1 | |
| SCHEMBL4189770 | 0.62 | ALDH1A1 (0.36) | MEN1KMT2AATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |