Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CCR1 | P32246 | 3/20 | 0.56 |
| ▸ | CCR5 | P51681 | 3/20 | 0.56 |
| ▸ | CCR8 | P51685 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29871258 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL31126641 | 0.87 | MEN1 (0.56) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL10837840 | 0.87 | MEN1 (0.56) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| 1-Naphthoquinoline SCHEMBL27520089 | 0.81 | LMNA (0.55) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| 1-Naphthoquinoline SCHEMBL28583281 | 0.79 | LMNA (0.67) | ALDH1A1LMNASMN1; SMN2KDM4ECCR1 | |
| 1-Naphthoquinoline SCHEMBL28190950 | 0.79 | LMNA (0.67) | ALDH1A1LMNASMN1; SMN2KDM4ECCR1 | |
| 1-Naphthoquinoline SCHEMBL27675599 | 0.79 | LMNA (0.56) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL170181 | 0.79 | LMNA (0.61) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| 1-Naphthoquinoline SCHEMBL27725047 | 0.78 | LMNA (0.64) | ALDH1A1LMNASMN1; SMN2KDM4ECCR1 | |
| 1-Naphthoquinoline SCHEMBL29533982 | 0.77 | LMNA (0.69) | ALDH1A1LMNASMN1; SMN2KDM4ECCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917903-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11917903-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-20210111345-A1 | METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2021-04-15 | — | — | US | disclosed |
| WO-2019179909-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210111345-A1 | METAL COMPLEXES | NCLN, BICRA, AP3M1 | ALDH1A1 4579/4885MEN1 1112/4885KMT2A 2978/4885 |
| US-11917903-B2 | Metal complexes | NCLN, BICRA, AP3M1 | ALDH1A1 4579/4885MEN1 1112/4885KMT2A 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.