Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 5/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 5/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 4/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390956 | 0.97 | RORC (0.33) | RORCL3MBTL1GAAALOX15ALDH1A1 | |
| SCHEMBL21390770 | 0.90 | ALDH1A1 (0.31) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL21391133 | 0.87 | CYP11B1 (0.33) | L3MBTL1ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL21391155 | 0.83 | ACSS2 (0.39) | ALDH1A1TNKSPARP2ACSS2HDAC1 | |
| SCHEMBL21390755 | 0.82 | RORC (0.40) | RORCSMN1; SMN2TNKSPARP2ACSS2 | |
| SCHEMBL21390756 | 0.82 | — | — | |
| SCHEMBL21391072 | 0.82 | PDE10A (0.34) | ALDH1A1TNKSPARP2ACSS2PARP1 | |
| SCHEMBL21390955 | 0.81 | ALDH1A1 (0.32) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL20624116 | 0.80 | EGFR (0.36) | RORCALDH1A1SMN1; SMN2NPSR1ACSS2 | |
| SCHEMBL19276102 | 0.80 | EGFR (0.36) | RORCALDH1A1SMN1; SMN2NPSR1ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |