Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 6/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390680 | 0.97 | HDAC1 (0.36) | HDAC1PIK3CAPRKDCBRD4CREBBP | |
| SCHEMBL21390672 | 0.86 | BRD4 (0.34) | HDAC1PIK3CAPRKDCBRD4CREBBP | |
| SCHEMBL23132031 | 0.83 | CYP11B2 (0.41) | HDAC1 | |
| SCHEMBL21390681 | 0.83 | BRD4 (0.35) | HDAC1BRD4 | |
| SCHEMBL21390884 | 0.82 | BRD4 (0.33) | HDAC1BRD4IDH1 | |
| SCHEMBL23132028 | 0.80 | BRD4 (0.35) | HDAC1BRD4 | |
| SCHEMBL21354567 | 0.79 | ALK (0.41) | IDH1 | |
| SCHEMBL21390697 | 0.78 | BRD4 (0.33) | BRD4CREBBPACACB | |
| SCHEMBL21390928 | 0.78 | HPGDS (0.36) | HDAC1ACACBIDH1HPGDS | |
| SCHEMBL21390826 | 0.77 | CACNA1H (0.35) | HDAC1BRD4CREBBPACACBIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |