Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391065 | 0.87 | RORC (0.35) | RORCEPHX2IDH1 | |
| SCHEMBL21391177 | 0.87 | RORC (0.32) | RORCTLR8TLR7HDAC1 | |
| SCHEMBL21391168 | 0.85 | RORC (0.35) | RORCCACNA1GCACNA1HHDAC1 | |
| SCHEMBL23132029 | 0.83 | HDAC1 (0.33) | RORCHDAC1 | |
| SCHEMBL21390935 | 0.81 | HDAC1 (0.33) | RORCHDAC1 | |
| SCHEMBL18791696 | 0.80 | ALK (0.36) | RORCEPHX2ARCACNA1GCACNA1H | |
| SCHEMBL21391108 | 0.79 | CACNA1H (0.36) | RORCCACNA1GCACNA1HHDAC1 | |
| SCHEMBL21391118 | 0.78 | CACNA1G (0.35) | RORCCACNA1GCACNA1HHDAC1 | |
| SCHEMBL21390804 | 0.77 | CACNA1G (0.34) | RORCCACNA1GCACNA1HHDAC1 | |
| SCHEMBL21391034 | 0.77 | TNKS (0.32) | RORCHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |