Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391176 | 0.86 | HDAC1 (0.32) | HDAC1 | |
| SCHEMBL21391064 | 0.85 | RORC (0.37) | RORCHDAC1CACNA1GCACNA1H | |
| SCHEMBL21391108 | 0.85 | CACNA1H (0.36) | RORCHDAC1CACNA1GCACNA1H | |
| SCHEMBL21391118 | 0.83 | CACNA1G (0.35) | RORCHDAC1CACNA1GCACNA1H | |
| SCHEMBL21391171 | 0.81 | BRD4 (0.39) | RORCHDAC1 | |
| SCHEMBL21391164 | 0.81 | CDK4 (0.35) | HDAC1 | |
| SCHEMBL21390754 | 0.81 | NOS1 (0.33) | — | |
| SCHEMBL21391177 | 0.79 | RORC (0.32) | RORCHDAC1 | |
| SCHEMBL18779271 | 0.79 | EGFR (0.36) | RORCCACNA1GCACNA1H | |
| SCHEMBL21390804 | 0.78 | CACNA1G (0.34) | RORCHDAC1CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |