Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | BRD4 | O60885 | 5/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391065 | 0.91 | RORC (0.35) | TNKSPARP1PARP2KDM4EALDH1A1 | |
| SCHEMBL21391177 | 0.89 | RORC (0.32) | HDAC1RORC | |
| SCHEMBL21391163 | 0.89 | CYP19A1 (0.32) | ALDH1A1ACSS2HDAC1BRD4CREBBP | |
| SCHEMBL21390935 | 0.89 | HDAC1 (0.33) | HDAC1BRD4CREBBPRORC | |
| SCHEMBL21391061 | 0.87 | ACSS2 (0.33) | ACSS2HDAC1BRD4CREBBP | |
| SCHEMBL23132029 | 0.86 | HDAC1 (0.33) | KDM4EALDH1A1HPGDHDAC1BRD4 | |
| SCHEMBL21390669 | 0.86 | CYP11B2 (0.39) | TNKSPARP1PARP2KDM4EALDH1A1 | |
| SCHEMBL21391062 | 0.85 | ACSS2 (0.33) | ACSS2 | |
| SCHEMBL21390668 | 0.81 | HDAC1 (0.35) | TNKSPARP1PARP2KDM4EALDH1A1 | |
| SCHEMBL21391060 | 0.81 | HDAC1 (0.36) | ACSS2HDAC1RORCCPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |