Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391034 | 0.91 | TNKS (0.32) | RORCTNKSPARP1PARP2KDM4E | |
| SCHEMBL21391064 | 0.87 | RORC (0.37) | RORCEPHX2IDH1 | |
| SCHEMBL21390804 | 0.87 | CACNA1G (0.34) | RORCTNKSPARP1PARP2ACSS2 | |
| SCHEMBL21390669 | 0.81 | CYP11B2 (0.39) | RORCTNKSPARP1PARP2KDM4E | |
| SCHEMBL20111388 | 0.81 | EGFR (0.38) | RORCKDM4EALDH1A1HPGDHIF1A | |
| SCHEMBL18791699 | 0.81 | EGFR (0.38) | RORCKDM4EALDH1A1HPGDHIF1A | |
| SCHEMBL21390758 | 0.81 | HTR3A (0.31) | ALDH1A1 | |
| SCHEMBL21391163 | 0.81 | CYP19A1 (0.32) | ALDH1A1ACSS2 | |
| SCHEMBL21391169 | 0.81 | BRD4 (0.38) | IDH1 | |
| SCHEMBL21391177 | 0.80 | RORC (0.32) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |