Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390678 | 0.86 | TRPV4 (0.32) | — | |
| SCHEMBL21390967 | 0.84 | — | — | |
| SCHEMBL21391106 | 0.83 | HDAC1 (0.37) | — | |
| SCHEMBL21390925 | 0.83 | HPGDS (0.34) | — | |
| SCHEMBL21391109 | 0.83 | — | — | |
| SCHEMBL21390693 | 0.82 | ACSS2 (0.31) | — | |
| SCHEMBL21391033 | 0.81 | ACSS2 (0.33) | APEX1 | |
| SCHEMBL21391003 | 0.81 | — | — | |
| SCHEMBL21390957 | 0.80 | NTRK1 (0.33) | APEX1 | |
| SCHEMBL18779202 | 0.79 | ALK (0.34) | POLBAPEX1KARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |