Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.39 |
| ▸ | IDH1 | O75874 | 8/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391169 | 0.90 | BRD4 (0.38) | BRD4IDH1HDAC1 | |
| SCHEMBL21391168 | 0.81 | RORC (0.35) | HDAC1RORC | |
| SCHEMBL21390844 | 0.81 | IDH1 (0.35) | BRD4IDH1HDAC1 | |
| SCHEMBL21391176 | 0.81 | HDAC1 (0.32) | BRD4HDAC1 | |
| SCHEMBL21391035 | 0.80 | HDAC1 (0.35) | BRD4IDH1HDAC1 | |
| SCHEMBL18791660 | 0.79 | BRD4 (0.40) | BRD4IDH1 | |
| SCHEMBL21390880 | 0.77 | HDAC1 (0.37) | HDAC1RORC | |
| SCHEMBL21390803 | 0.77 | CCNT1 (0.35) | HDAC1 | |
| SCHEMBL21390920 | 0.76 | RORC (0.33) | HDAC1RORC | |
| SCHEMBL21391073 | 0.76 | PDE10A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |