Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390803 | 0.81 | CCNT1 (0.35) | HDAC1CCNT1CDK9HDAC3HDAC4 | |
| SCHEMBL23132031 | 0.80 | CYP11B2 (0.41) | HDAC1AGTR1AGTR2 | |
| SCHEMBL21391108 | 0.78 | CACNA1H (0.36) | HDAC1RORC | |
| SCHEMBL18779205 | 0.77 | CCNT1 (0.40) | CCNT1CDK9 | |
| SCHEMBL21391171 | 0.77 | BRD4 (0.39) | HDAC1RORC | |
| SCHEMBL21390668 | 0.77 | HDAC1 (0.35) | HDAC1CCNT1CDK9HDAC6 | |
| SCHEMBL21390680 | 0.76 | HDAC1 (0.36) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL21391106 | 0.75 | HDAC1 (0.37) | HDAC1RORC | |
| SCHEMBL21390845 | 0.75 | HDAC1 (0.40) | HDAC1RORC | |
| SCHEMBL21390929 | 0.75 | RORC (0.30) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |