Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.38 |
| ▸ | IDH1 | O75874 | 9/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391171 | 0.90 | BRD4 (0.39) | BRD4IDH1HDAC1 | |
| SCHEMBL21391036 | 0.88 | HDAC1 (0.35) | IDH1HDAC1 | |
| SCHEMBL21391060 | 0.82 | HDAC1 (0.36) | HDAC1 | |
| SCHEMBL21391063 | 0.82 | HDAC1 (0.36) | HDAC1 | |
| SCHEMBL20111001 | 0.81 | EGFR (0.40) | IDH1 | |
| SCHEMBL21390804 | 0.81 | CACNA1G (0.34) | BRD4HDAC1 | |
| SCHEMBL18791663 | 0.81 | EGFR (0.40) | IDH1 | |
| SCHEMBL21391170 | 0.81 | KDM2B (0.33) | — | |
| SCHEMBL21391065 | 0.81 | RORC (0.35) | IDH1 | |
| SCHEMBL21390669 | 0.81 | CYP11B2 (0.39) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |