Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.33 |
| ▸ | APLNR | P35414 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391133 | 0.81 | CYP11B1 (0.33) | KMT2AL3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL20624354 | 0.80 | CXCR6 (0.35) | DRD2KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL19277847 | 0.80 | CXCR6 (0.35) | DRD2KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL19276253 | 0.80 | CXCR6 (0.35) | DRD2KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL21390770 | 0.80 | ALDH1A1 (0.31) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL21391036 | 0.80 | HDAC1 (0.35) | APLNRSMN1; SMN2 | |
| SCHEMBL21391172 | 0.80 | ACSS2 (0.33) | BRD4CREBBP | |
| SCHEMBL21390956 | 0.80 | RORC (0.33) | L3MBTL1ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL21391169 | 0.80 | BRD4 (0.38) | BRD4 | |
| SCHEMBL21391137 | 0.79 | AGTR2 (0.34) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |