Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 4/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391172 | 0.90 | ACSS2 (0.33) | ACSS2HDAC1BRD4CREBBP | |
| SCHEMBL21391163 | 0.90 | CYP19A1 (0.32) | ACSS2HDAC1BRD4CREBBP | |
| SCHEMBL21391034 | 0.87 | TNKS (0.32) | ACSS2HDAC1BRD4CREBBP | |
| SCHEMBL21391063 | 0.85 | HDAC1 (0.36) | ACSS2HDAC1 | |
| SCHEMBL21391060 | 0.85 | HDAC1 (0.36) | ACSS2HDAC1 | |
| SCHEMBL21391178 | 0.85 | HDAC1 (0.30) | HDAC1 | |
| SCHEMBL21390669 | 0.81 | CYP11B2 (0.39) | ACSS2HDAC1 | |
| SCHEMBL18792006 | 0.80 | EGFR (0.37) | ACSS2 | |
| SCHEMBL20110984 | 0.80 | EGFR (0.37) | ACSS2 | |
| SCHEMBL18791999 | 0.80 | EGFR (0.37) | ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |