Sugi Predict

Sugi Predict / Compounds / SCHEMBL2139192

SCHEMBL2139192

SCHEMBL2139192

N#CC(C(=O)Cl)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.47
▸ MAPT P10636 5/20 0.47
▸ LMNA P02545 4/20 0.47
▸ MAPK1 P28482 3/20 0.47
▸ NPSR1 Q6W5P4 3/20 0.47
▸ XBP1 P17861 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ HTT P42858 3/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ HPGD P15428 1/20 0.40
▸ CRHBP P24387 1/20 0.40
▸ CRHR2 Q13324 1/20 0.40
▸ ALOX12 P18054 1/20 0.40
▸ NPY1R P25929 1/20 0.40
▸ NPY2R P49146 1/20 0.40
▸ CES1 P23141 4/20 0.39
▸ CES2 O00748 3/20 0.39
▸ TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL269364 0.83 ALDH1A1 (0.50) ALDH1A1MAPTLMNAMAPK1NPSR1
Water SCHEMBL11778081 0.83 ALDH1A1 (0.50) ALDH1A1MAPTLMNAMAPK1NPSR1
SCHEMBL10595234 0.82 ALDH1A1 (0.49) ALDH1A1MAPTLMNAMAPK1NPSR1
SCHEMBL9858054 0.81 CES2 (0.43) ALDH1A1LMNANPSR1RAB9AHTT
Ethane SCHEMBL5679245 0.80 ALDH1A1 (0.51) ALDH1A1MAPTLMNAMAPK1NPSR1
SCHEMBL10061925 0.80 ALDH1A1 (0.51) ALDH1A1MAPTLMNAMAPK1NPSR1
Ethylene SCHEMBL28481468 0.80 ALDH1A1 (0.47) ALDH1A1MAPTLMNAMAPK1NPSR1
SCHEMBL548316 0.80 ALDH1A1 (0.47) ALDH1A1MAPTLMNAMAPK1NPSR1
SCHEMBL9717134 0.79 ALDH1A1 (0.52) ALDH1A1MAPTLMNAMAPK1NPSR1
SCHEMBL30530599 0.77 ALDH1A1 (0.45) ALDH1A1MAPTLMNAMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0345591-A1 Propanol amine derivatives F. HOFFMANN-LA ROCHE AG (CH) 1989-12-13 — — EP claimed
EP-4543872-A1 MULTI-PHOTOPROTECTIVE COMPOUNDS AND USES THEREOF SKINOSIVE (FR) 2025-04-30 — — EP disclosed
WO-2023247598-A1 MULTI-PHOTOPROTECTIVE COMPOUNDS AND USES THEREOF SKINOSIVE (FR) 2023-12-28 — — WO disclosed
EP-2373158-A2 AGROCHEMICAL COMPOSITION COMPRISING PESTICIDE AND UV ABSORBER BASF SE (DE) 2011-10-12 — — EP disclosed
US-20110237665-A1 Agrochemical Composition Comprising Pesticide and UV Absorber BASF SE (DE) 2011-09-29 — — US disclosed
US-20110237665-A1 Agrochemical Composition Comprising Pesticide and UV Absorber BASF SE (DE) 2011-09-29 — — US disclosed
US-20110237665-A1 Agrochemical Composition Comprising Pesticide and UV Absorber BASF SE (DE) 2011-09-29 — — US disclosed
US-7863478-B2 1,3-Bis-[3-(4-methoxyphenyl)-2-propenoyloxy]-2-oxopropane; novel alpha-hydroxyketone derivatives as light-protection filters for cosmetic or drug products; used in cosmetic protective coatings; solar radiation; sunscreen agents; aging resistance; wrinkle resistance; food additives; dermatology MERCK PATENT GMBH (DE) 2011-01-04 — — US disclosed
US-20100184887-A1 HYBRID NANOPARTICLES BASF SE (DE) 2010-07-22 — — US disclosed
US-20100184887-A1 HYBRID NANOPARTICLES BASF SE (DE) 2010-07-22 — — US disclosed
US-5272219-A Process for preparing amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-12-21 — — US disclosed
US-5162405-A Single-functional and mixtures of multi-functional oligomeric performance additive compositions and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-11-10 — — US disclosed
EP-0472819-A2 Polymeric peroxides derived from hydroxy-hydroperoxides and dihydroxy-dialkyl peroxides and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-03-04 — — EP disclosed
US-5039754-A Block copolymer;compatibilizing polymer blends and alloy ATOCHEM NORTH AMERICA, INC. (US) 1991-08-13 — — US disclosed
US-5013777-A Benzosulfonic acids as end groups of engineering thermoplastic resins; fireproofing; oxidation and UV resistances; photostabilizers ATOCHEM NORTH AMERICA, INC. (US) 1991-05-07 — — US disclosed
US-4956416-A CURING UNSATURATED POLYESTERS; ADDITION POLYMERIZATION CATALYSTS; COAVALENTLY BOUND PERFORMANCE ADDITIVE FUNCTIONS; GRAFT AND BLOCK POLYMERS; SELF-CURING ATOCHEM NORTH AMERICA, INC. (US) 1990-09-11 — — US disclosed
EP-0355733-A1 Amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1990-02-28 — — EP disclosed
EP-0332761-A2 Single-functional and mixtures of multifunctional oligomeric performance additive compositions, and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-09-20 — — EP disclosed
US-4368241-A Alkoxysilanes and method for making GENERAL ELECTRIC COMPANY (US) 1983-01-11 — — US disclosed
US-4307240-A Alkoxysilanes and method for making GENERAL ELECTRIC COMPANY (US) 1981-12-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237665-A1 Agrochemical Composition Comprising Pesticide and UV Absorber DDT, CRY1, STOM ALDH1A1 695/4885MAPT 886/4885LMNA 4116/4885
US-20100184887-A1 HYBRID NANOPARTICLES RAB5IF, TTPA, PRNP ALDH1A1 182/4885MAPT 11/4885LMNA 398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.