Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.41 |
| ▸ | PRKACA | P17612 | 4/20 | 0.41 |
| ▸ | GSK3A | P49840 | 4/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.41 |
| ▸ | CDC42BPA | Q5VT25 | 4/20 | 0.41 |
| ▸ | CDK1 | P06493 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | PRKX | P51817 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509447 | 0.81 | NR4A2 (0.47) | NR4A2HDAC8CHEK1NR1D1CAPN1 | |
| SCHEMBL19871248 | 0.79 | ALDH1A1 (0.46) | NR4A2HDAC8ROCK2PRKACAGSK3A | |
| SCHEMBL19872791 | 0.78 | RXRA (0.43) | NR4A2HDAC8ROCK2PRKACAGSK3A | |
| SCHEMBL24143779 | 0.76 | NR1D1 (0.50) | NR4A2HDAC8GSK3BDYRK1ACHEK1 | |
| SCHEMBL24143036 | 0.76 | HTR2A (0.54) | NR4A2GSK3BDYRK1ACHEK1NR1D1 | |
| SCHEMBL11657252 | 0.73 | NR4A2 (0.58) | NR4A2ROCK2PRKACAGSK3APRKCD | |
| SCHEMBL10474583 | 0.73 | CAPN1 (0.65) | NR4A2ROCK2PRKACAGSK3APRKCD | |
| SCHEMBL19872648 | 0.73 | NR4A2 (0.46) | NR4A2HDAC8ROCK2PRKACAGSK3A | |
| SCHEMBL20935033 | 0.72 | NR4A2 (0.56) | NR4A2NR1D1CCNCCDK8CNR1 | |
| SCHEMBL24143303 | 0.71 | NR1D1 (0.73) | NR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-08-03 | — | — | US | disclosed |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | POR, CYP4F3, CBR3 | NR4A2 2797/4885HDAC8 4050/4885ROCK2 2297/4885 |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | POR, CYP4F3, CBR3 | NR4A2 2797/4885HDAC8 4050/4885ROCK2 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.