Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21387714 | 0.78 | CTPS1 (0.41) | CTPS1 | |
| SCHEMBL21392042 | 0.75 | HPGD (0.33) | — | |
| SCHEMBL21387657 | 0.72 | CTPS1 (0.34) | CTPS1 | |
| SCHEMBL5768666 | 0.72 | PDPK1 (0.36) | — | |
| SCHEMBL21387600 | 0.71 | CTPS1 (0.31) | CTPS1 | |
| SCHEMBL21387698 | 0.71 | HTR3A (0.32) | CTPS1 | |
| SCHEMBL21392165 | 0.71 | ACACB (0.39) | — | |
| SCHEMBL21392182 | 0.70 | CTPS1 (0.33) | CTPS1 | |
| SCHEMBL21391982 | 0.70 | — | — | |
| SCHEMBL21392118 | 0.69 | CTSK (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180244-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019179652-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |