Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392071 | 0.75 | CTPS1 (0.31) | — | |
| SCHEMBL22482055 | 0.72 | PGK1 (0.43) | — | |
| SCHEMBL15332206 | 0.70 | KMT2A (0.42) | HPGD | |
| SCHEMBL8028444 | 0.69 | ADORA2A (0.36) | — | |
| SCHEMBL24862870 | 0.67 | GRM5 (0.40) | — | |
| SCHEMBL29952585 | 0.66 | CCR2 (0.42) | — | |
| SCHEMBL20730061 | 0.64 | PGK1 (0.41) | — | |
| SCHEMBL3363182 | 0.64 | CYP3A4 (0.42) | HPGD | |
| SCHEMBL247492 | 0.64 | SMN1; SMN2 (0.44) | HPGD | |
| SCHEMBL4287573 | 0.64 | MBOAT4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179652-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019180244-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |