SCHEMBL21392418

SCHEMBL21392418

CCc1nc2ccccc2n1-c1ccc(-c2c3ccccc3c(-c3cc(-c4ccccc4)cc(-c4ccccc4)c3)c3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.46
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
PDE10A Q9Y233 4/20 0.42
CYP1A2 P05177 1/20 0.42
NTRK1 P04629 1/20 0.40
NTRK2 Q16620 1/20 0.40
RECQL P46063 1/20 0.40
BMI1 P35226 1/20 0.39
POLB P06746 1/20 0.39
HSP90AA1 P07900 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26343681 1.00 ALDH1A1 (0.46) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL24673731 0.96 ALDH1A1 (0.43) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL879276 0.95 MEN1 (0.50) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL26343653 0.95 MEN1 (0.50) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL2604840 0.95 MEN1 (0.50) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL25769019 0.95 MEN1 (0.50) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL29449951 0.95 MEN1 (0.50) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL26343756 0.94 KDM4E (0.45) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL21392538 0.94 KDM4E (0.45) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL17341687 0.94 MEN1 (0.51) ALDH1A1MEN1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244871-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244871-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244970-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244970-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed
US-20190296238-A1 Organic Light-emitting Element LG CHEM, LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296238-A1 Organic Light-emitting Element CRY1, CRY2, NR2E3 ALDH1A1 567/4885MEN1 1414/4885MAPT 665/4885
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 ALDH1A1 115/4885MEN1 480/4885MAPT 1419/4885
US-11877509-B2 Organic light-emitting element CRY1, CRY2, NR2E3 ALDH1A1 567/4885MEN1 1414/4885MAPT 665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.